Tanaji T. Talele

Professor of Medicinal Chemistry
PhD, Medicinal Chemistry, UICT (formerly UDCT), 1999MS, Medicinal Chemistry, UICT (formerly UDCT), 1994BS, Pharmacy, College of Pharmacy, University of Pune, 1992

Tanaji Talele received his B.S. degree in pharmacy from the University of Pune in 1992. He then went on to receive his M.S. (1994) and Ph.D. (1998) degrees from the University of Mumbai, both in Medicinal Chemistry. In 2005, Professor Talele joined the College of Pharmacy and Health Sciences at St. John’s University as an Assistant Professor of Medicinal Chemistry, where he was promoted to Associate Professor in 2009 and to full Professor in 2014. Principal research efforts in his group include the development of small molecule inhibitors of poly(ADP-ribose) polymerases (PARPs), histone deacetylases (HDACs) and RAD51 for the treatment of cancer. His research combines tools from organic synthesis, structural biology and molecular modeling. He has published 91 articles in peer-reviewed journals, including J. Med. Chem., Eur J. Med. Chem., Bioorg. Med. Chem., Bioorg. Med. Chem. Lett., Molecules, ChemBioChem, Biochem Pharm., Cancer Lett., Leukemia, PLoS ONE, Mol. Pharmacol., and Molecular Pharm. Since 2016, he has been serving as an editorial advisory board member of the Eur. J. Med. Chem., and previously served on the editorial advisory board of the J. Chem. In 2018 he was appointed as an Editor of Bioorg. Chem. Since 2005, he has graduated 6 Ph.D. and 10 M.S. students in the field of medicinal chemistry. Currently he is mentoring one graduate student, two postdoc researchers and number of undergraduate students.

  • Structure-based development of small molecule inhibitors of PARP, HDAC and RAD51
  • UCSF funding for immuno-oncology project