Faculty Innovations Supported By The Venture & Innovation Center (VIC)

Dr Vivek Gupta - CPHS

Enhanced Delivery & Effectiveness of Drug Delivery Using Cyclodextrin - This invention presents a new approach to improve the delivery and effectiveness of certain drugs that are difficult to absorb in the body. The study shows that formulating these drugs with cyclodextrins (a type of carbohydrate) and weak acids can significantly boost their solubility, ability to pass through cell membranes, and overall performance in the body. This addresses challenges of poor water solubility and drug transport that limit the effectiveness of many pharmaceutical compounds. The formulations were found to be safe and compatible with biological systems. This innovation has important implications for developing more effective oral medications, particularly for drugs that currently struggle with low absorption.

Dr Nitesh Kunda  - CPHS

New Way to Deliver Imipenem for the Treatment of Lung Bacterial Infections – This innovation develops a new way to deliver an antibiotic called imipenem directly to the lungs. Imipenem is used to treat lung infections caused by a bacteria called Pseudomonas aeruginosa. The key challenges were making imipenem more stable and improving how it can be inhaled as a dry powder. By adding an ingredient called L-leucine, the formulation became more stable, easy to manufacture, and able to reach the lungs better. This approach offers a localized treatment that can achieve therapeutic effects in the lungs at lower doses, potentially reducing systemic side effects. Further, in vitro bacterial studies showed excellent efficacy. The innovation is still in early development but shows great promise for further advancement.

Dr Hyunah Cho - formerly CPHS

Waterless Personal Care & Skincare Products in Tablet Form – This innovation focuses on developing a line of waterless personal care and skincare products in the form of portable, shelf-stable tablets. The products include soap, haircare, spot treatments, and customizable skincare options. Formulating these products without water aims to reduce storage space, transportation fuel, and environmental impact compared to traditional water-based formulations. The tablets can be easily transported, crushed, and activated with water. Key benefits include portability, sustainability, hygiene, and extended shelf-life without added preservatives. This innovation provides an alternative to conventional water-containing personal care and skincare products.