Vikas V. Dukhande
PhD, Idaho State University
BS, Pharmaceutical Sciences, Institute of Chemical Technology, Mumbai University
Raththagala, M., Brewer, M. K., Parker, M. W., Sherwood, A. R., Wong, B. K., Hsu, S., Bridges, T. M., Paasch, B. C., Hellman, L. M., Husodo, S., Meekins, D. A., Taylor, A. O., Turner, B. D., Auger, K. D., Dukhande, V. V., Chakravarthy, S., Sanz, P., Woods, Jr, V. L., Li , S., Vander Kooi, C. W., and Gentry, M. S. (2015). Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease.. Molecular cell. vol. 57, pp. 261-72.
Jang, E. R., Shi, P., Bryant, J., Chen, J., Dukhande, V. V., Gentry, M. S., Jang, H., Jeoung, M., and Galperin, E. (2014). HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.. Molecular and cellular biology. vol. 34, pp. 3579-93.
Dukhande, V. V., Kawikova, I., Bothwell, A. L., and Lai, J. C. (2013). Neuroprotection against neuroblastoma cell death induced by depletion of mitochondrial glutathione.. Apoptosis : an international journal on programmed cell death. vol. 18, pp. 702-12.
Dukhande, V. V., Sharma, G. C., Lai, J. C., and Farahani, R. (2011). Chronic hypoxia-induced alterations of key enzymes of glucose oxidative metabolism in developing mouse liver are mTOR dependent.. Molecular and cellular biochemistry. vol. 357, pp. 189-97.
Romá-Mateo, C., Solaz-Fuster Mdel, C., Gimeno-Alcañiz, J. V., Dukhande, V. V., Donderis, J., Worby, C. A., Marina, A., Criado, O., Koller, A., De Rodriguez Cordoba, S., Gentry, M. S., and Sanz, P. (2011). Laforin, a dual-specificity phosphatase involved in Lafora disease, is phosphorylated at Ser25 by AMP-activated protein kinase.. The Biochemical journal. vol. 439, pp. 265-75.
Dukhande, V. V., Rogers, D. M., Romá-Mateo, C., Donderis, J., Marina, A., Taylor, A. O., Sanz, P., and Gentry, M. S. (2011). Laforin, a dual specificity phosphatase involved in Lafora disease, is present mainly as monomeric form with full phosphatase activity.. PloS one. vol. 6, pp. e24040.
Lai, J. C., Ananthakrishnan, G., Jandhyam, S., Dukhande, V. V., Bhushan, A., Gokhale, M., Daniels, C. K., and Leung, S. W. (2010). Treatment of human astrocytoma U87 cells with silicon dioxide nanoparticles lowers their survival and alters their expression of mitochondrial and cell signaling proteins.. International journal of nanomedicine. vol. 5, pp. 715-23.
Lai, J. C., Lai, M. B., Jandhyam, S., Dukhande, V. V., Bhushan, A., Daniels, C. K., and Leung, S. W. (2008). Exposure to titanium dioxide and other metallic oxide nanoparticles induces cytotoxicity on human neural cells and fibroblasts.. International journal of nanomedicine. vol. 3, pp. 533-45.
Isaac, A. O., Dukhande, V. V., and Lai, J. C. (2007). Metabolic and antioxidant system alterations in an astrocytoma cell line challenged with mitochondrial DNA deletion.. Neurochemical research. vol. 32, pp. 1906-18.
Dukhande, V. V., Malthankar-Phatak, G. H., Hugus, J. J., Daniels, C. K., and Lai, J. C. (2006). Manganese-induced neurotoxicity is differentially enhanced by glutathione depletion in astrocytoma and neuroblastoma cells.. Neurochemical research. vol. 31, pp. 1349-57.