Frank A. Barile, Ph.D.

Pharmaceutical Sciences
College of Pharmacy and Allied Health Professions

Clinical Toxicology: Principles and Mechanisms
Publisher: CRC Press
New York, NY
2004, 441 pages

The book examines the complex interactions associated with clinical toxicological events as a result of therapeutic drug administration or deliberate or inadvertent chemical exposure. Special emphasis is placed on signs and symptoms of syndromes and pathology caused by chemical exposure and administration of clinical drugs. Source, pharmacological and toxicological mechanism of action, toxicokinetics, medicinal chemistry, clinical management of toxicity, and detection and identification of the drug or chemical in body fluids, are discussed.

. . . In short, this book is an excellent resource for teachers, clinical and forensic toxicologists, and physicians practicing emergency medicine.
- James F. Wesley, Monroe County Crime Laboratory