Research Areas: Bioinformatics, toxicogenomics and the
development of proteomic screens to identify protein networks
effected by toxicants, drugs, or novel peptides. Our model system
examines the neuronal SNARE complex of proteins that drive vesicle
membrane fusion and neurotransmitter release.
Joshi-Tope G, Gillespie M, Vastrik I, D'Eustachio P, Schmidt E,
de Bono B, Jassal B, Gopinath GR, Wu GR, Matthews L, Lewis S,
Birney E, Stein L. (2005). Reactome: A Knowledgebase of Biological
Pathways. Nucleic Acids Res 1;33(Database issue):D428-32.
Joshi-Tope, G., I. Vastrik, et al. (2003). "The Genome
Knowledgebase: a resource for biologists and bioinformaticists."
Cold Spring Harb Symp Quant Biol 68: 237-43.
Gillespie M. “Mitochrondrial fatty acid beta-oxidation of
saturated fatty acids.” Genome Knowledgebase
2003.
Gillespie M. “Affordable proteomics: the two-hybrid systems.” Curr
Opin Mol Ther 2003;5(3):266-270.
Gillespie, M (2003) Affordable proteomics: The two-hybrid
systems. Current Opinion in Molecular Therapeutics 2003
5(3):266-270
Gillespie, M (2003) Two-Hybrid Proteomics: Leveraging
Small-Scale Proteomic Techniques to Take Advantage of Large-Scale
Databases. Preclinica, 2003 May/June 37-41
Carvalho, F. and M. E. Gillespie (2003). "Bringing Proteomics
Into the Lab - Proteomics Lab 101." Biochemistry and Molecular
Biology Education, 2003 31: 46-51.