More Information

Vivek Gupta

Assistant Professor
Pharmaceutical Sciences
PhD, Pharmaceutical Sciences, Texas Tech University Health Sciences Center
BS, Pharmaceutical Sciences, Jamia Hamdard (University)
Dr Vivek Gupta joined St. John's University College of Pharmacy and Health Sciences as an assistant professor of industrial pharmacy in September 2016. Prior to joining SJU, Dr Gupta was an assistant professor of pharmaceutics at Keck Graduate Institute School of Pharmacy in Claremont, CA (2013-2016). Dr Gupta holds a PhD in pharmaceutical sciences from Texas Tech University HSC (2010) along with postdoctoral research experience in chemical engineering at University of California Santa Barbara (2011-2013). Dr Gupta's is a trained pharmaceutical researcher with interests in the areas of non-invasive delivery of small and macromolecules via oral and inhalational routes. He has published many peer reviewed research articles in high-impact journals like Nature Nanotechnology, PNAS, ACS Nano, Biomaterials and Journal of Controlled Release to name a few. Dr. Gupta's current research focuses on drug repositioning for respiratory disorders including pulmonary hypertension, and lung cancer; and on developing novel carriers for enhanced localized and systemic delivery of therapeutics.

Teaching Interests

Pharmaceutics, Pharmacokinetics, Biopharmaceutics

Research Interests

Non-invasive Drug Delivery, Nanotechnology, Oral Delivery, 3D Printing, Targeted Drug Delivery Systems, Pulmonary Hypertension, Lung cancer, Drug discovery and Repurposing

Courses Taught

PHS
3601
PHARMACEUTICS I FOR PHARMD
PHS
4602
BIOPHA & BASIC PHARMACOKINETIC

Select Publications

Journal Articles

Wibroe, P. P., Anselmo, A. C., Nilsson, P. H., Sarode, A., Gupta, V., Urbanics, R., Szebeni, J., Hunter, A. C., Mitragotri, S., Mollnes, T. E., and Moghimi, S. M. (2017). Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes.. Nature nanotechnology.

Vaidya, B., Pangallo, M., Ruffenach, G., Cunningham, C. M., Perron, J. C., Kolluru, S., Eghbali, M., and Gupta, V. (2017). Advances in treatment of pulmonary arterial hypertension: patent review.. Expert opinion on therapeutic patents.

Gupta, N., Liu, J. R., Patel, B., Solomon, D. E., Vaidya, B., and Gupta, V. (2016). Microfluidics‐based 3D cell culture models: Utility in novel drug discovery and delivery research. Bioengineering & Translational Medicine. vol. 1, pp. 63-81.

Gupta, V., Hwang, B., Doshi, N., Banerjee, A., Anselmo, A. C., and Mitragotri, S. (2016). Delivery of exenatide and insulin using mucoadhesive intestinal devices. Annals of biomedical engineering. vol. 44, pp. 1993-2007.

Vaidya, B., and Gupta, V. (2015). Novel therapeutic approaches for pulmonary arterial hypertension: Unique molecular targets to site-specific drug delivery. Journal of Controlled Release. vol. 211, pp. 118-133.

Zilbermintz, L., Leonardi, W., Jeong, S., Sjodt, M., McComb, R., Ho, C. C., Retterer, C., Gharaibeh, D., Zamani, R., and Soloveva, V. (2015). Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting. Scientific reports. vol. 5, pp. 13476.

Anselmo, A. C., Kumar, S., Gupta, V., Pearce, A. M., Ragusa, A., Muzykantov, V., and Mitragotri, S. (2015). Exploiting shape, cellular-hitchhiking and antibodies to target nanoparticles to lung endothelium: Synergy between physical, chemical and biological approaches. Biomaterials. vol. 68, pp. 1-8.

Anselmo, A. C., Gilbert, J. B., Kumar, S., Gupta, V., Cohen, R. E., Rubner, M. F., and Mitragotri, S. (2015). Monocyte-mediated delivery of polymeric backpacks to inflamed tissues: a generalized strategy to deliver drugs to treat inflammation. Journal of Controlled Release. vol. 199, pp. 29-36.

Gupta, V., Hwang, B. H., Lee, J., Anselmo, A. C., Doshi, N., and Mitragotri, S. (2013). Mucoadhesive intestinal devices for oral delivery of salmon calcitonin. Journal of Controlled Release. vol. 172, pp. 753-762.

Anselmo, A. C., Gupta, V., Zern, B. J., Pan, D., Zakrewsky, M., Muzykantov, V., and Mitragotri, S. (2013). Delivering nanoparticles to lungs while avoiding liver and spleen through adsorption on red blood cells. ACS nano. vol. 7, pp. 11129.

Gupta, V., Hwang, B. H., Doshi, N., and Mitragotri, S. (2013). A permeation enhancer for increasing transport of therapeutic macromolecules across the intestine. Journal of Controlled Release. vol. 172, pp. 541-549.

Gupta, V., Doshi, N., and Mitragotri, S. (2013). Permeation of Insulin, Calcitonin and Exenatide across Caco-2 Monolayers: Measurement Using a Rapid, 3-Day System. PLOS ONE. vol. 8, pp. e57136.

Gupta, V., Gupta, N., Shaik, I. H., Mehvar, R., Grayck, E. N., McMurtry, I. F., Oka, M., Komatsu, M., and Ahsan, F. (2013). Inhaled PLGA Particles of Prostaglandin E1 Ameliorate Symptoms and Progression of Pulmonary Hypertension at a Reduced Dosing Frequency. Molecular Pharmaceutics.

Gupta, V., and Ahsan, F. (2011). Influence of PEI as a core modifying agent on PLGA microspheres of PGE1, a pulmonary selective vasodilator. International journal of pharmaceutics.

Keywords: 
Pharmaceutics
Non-invasive and targeted drug delivery
Cardiopulmonary disorders
Drug discovery
Nanotechnology